Dopamine blocks inflammasome activation
نویسندگان
چکیده
منابع مشابه
NOX-free inflammasome activation.
In recent years, much has been learned about how the highly proinflammatory cytokines of the interleukin-1 (IL-1 ) cytokine family are regulated. These cytokines differ from other cytokines in that they are produced as biologically inactive proforms in the cytosol upon transcriptional induction. In a second step, the protease caspase-1 mediates the cleavage and release of the IL-1 family of cyt...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2015
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3817